Anti-EBF transcription factor 3 antibodies are used for the immunodetection of the protein encoded by the EBF3 gene. In humans, the canonical protein has a reported length of 596 amino acid residues and a mass of 64.9 kDa. Its subcellular localization is in the nucleus. Alternative splicing is reported to yield 2 different isoforms for this protein. It is reported to be expressed in the brain. A member of the COE protein family, it is known to be involved with the regulation of transcription. The gene encoding this protein is implicated in Hypotonia, ataxia, and delayed development syndrome. Other names for this target antigen include early B cell factor 3, olf-1/EBF-like 2, and transcription factor COE3. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.