Anti-SRY-box transcription factor 12 antibodies are used for the immunodetection of the protein encoded by the SOX12 gene. In humans, the canonical protein has a reported length of 315 amino acid residues and a mass of 34.1 kDa. Its subcellular localization is in the nucleus. It is noted to be expressed most abundantly in the CNS. It is reported to be a transcription factor that binds to DNA at the consensus sequence 5'-ACCAAAG-3' (By similarity). Other names for this target antigen include transcription factor SOX-12, SOX-22 protein, SRY (sex determining region Y)-box 12, SRY-box 12, SRY-related HMG-box gene 22, and SOX22. Gene orthologs have been identified in the mouse, rat, bovine, chimpanzee and chicken species.