Anti-colony stimulating factor 2 receptor subunit alpha antibodies are used for the immunodetection of the protein encoded by the CSF2RA gene. In humans, the canonical protein has a reported length of 400 amino acid residues and a mass of 46.2 kDa. Its subcellular localization is in the cell membrane and is secreted. Alternative splicing is reported to yield 8 different isoforms for this protein. A member of the Type I cytokine receptor protein family, it is known to be involved with cytokine-mediated signaling pathways and protein phosphorylation. Post-translational modifications have been described, including glycosylation. The gene encoding this protein is implicated in Pulmonary surfactant metabolism dysfunction. Other names for this target antigen include CDw116, CSF2R, CSF2RAX, CSF2RAY, CSF2RX, CSF2RY, GM-CSF-R-alpha, and CD116. Gene orthologs have been identified in the mouse, bovine and chimpanzee species.