Anti-cellular communication network factor 4 antibodies are used for the immunodetection of the protein encoded by the CCN4 gene. In humans, the canonical protein has a reported length of 367 amino acid residues and a mass of 40.3 kDa. It is known to be a secreted protein. Alternative splicing is reported to yield 5 different isoforms for this protein. It is found to be expressed in the heart, kidney, lung, pancreas, placenta, ovary, small intestine and spleen. A member of the CCN protein family, it is known to be involved with bone development and cell adhesion. Post-translational modifications have been described, including glycosylation. Other names for this target antigen include WISP1-OT1, WISP1-UT1, WISP1c, WISP1i, WISP1tc, CCN family member 4, WISP1 3'UTR-associated RNA 1, and WISP1. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.