Anti-nucleoporin 98 and 96 precursor antibodies are used for the immunodetection of the protein encoded by the NUP98 gene. In humans, the canonical protein has a reported length of 1817 amino acid residues and a mass of 197.6 kDa. Its subcellular localization is in the nucleus and membrane. Alternative splicing is reported to yield 6 different isoforms for this protein. A member of the Nucleoporin GLFG protein family, it is reported to play a role in the nuclear pore complex (NPC) assembly and/or maintenance. Post-translational modifications have been described, including protein cleavage. Other names for this target antigen include NUP196, NUP96, Nup98-96, nuclear pore complex protein Nup98-Nup96, nuclear pore complex protein Nup98, and ADIR2. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.