Anti-MCL1 apoptosis regulator, BCL2 family member antibodies are used for the immunodetection of the protein encoded by the MCL1 gene. In humans, the canonical protein has a reported length of 350 amino acid residues and a mass of 37.3 kDa. Its subcellular localization is in the membrane, nucleus, mitochondria, and cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of the Bcl-2 protein family, it is reported to be involved in regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Post-translational modifications have been described, including ubiquitination, protein cleavage and phosphorylation. Other names for this target antigen include EAT, MCL1-ES, MCL1L, MCL1S, TM, bcl2-L-3, mcl1/EAT, and BCL2L3. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species.