Anti-MMUT antibodies are used in the immunodetection of the protein methylmalonyl-CoA mutase. In humans, the canonical protein has a reported length of 750 amino acid residues and a mass of 83.1 kDa. Its subcellular localization is in the mitochondria and cytoplasm. It is notably widely expressed in many tissue types. A member of the Methylmalonyl-CoA mutase protein family, MMUT is known to catalyze the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle. The MMUT gene has been associated with the disease, Methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency. Synonyms for this target antigen include MUT, methylmalonyl-CoA mutase, mitochondrial, methylmalonyl Coenzyme A mutase, methylmalonyl-CoA isomerase, and MCM. MMUT gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.