Anti-CLN8 transmembrane ER and ERGIC protein antibodies are used for the immunodetection of the protein encoded by the CLN8 gene. In humans, the canonical protein has a reported length of 286 amino acid residues and a mass of 32.8 kDa. Its subcellular localization is in the ER. It is suspected to be play a role in cell proliferation during neuronal differentiation and in protection against cell death. Post-translational modifications have been described, including N-glycosylation. The gene encoding this protein is implicated in Ceroid lipofuscinosis. Other names for this target antigen include EPMR, TLCD6, protein CLN8, ceroid-lipofuscinosis, neuronal 8, and C8orf61. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.