Anti-Anoctamin 1 antibodies are used for the immunodetection of the protein encoded by the ANO1 gene. In humans, the canonical protein has a reported length of 986 amino acid residues and a mass of 114.1 kDa. Its subcellular localization is in the cell membrane. Alternative splicing is reported to yield 5 different isoforms for this protein. It is reported to be expressed in nasal epithelial cells. A member of the Anoctamin protein family, it is known to be involved with the transport of ions. Post-translational modifications have been described, including glycosylation. The gene encoding this protein is implicated in Intestinal dysmotility syndrome. Other names for this target antigen include INDMS, ORAOV2, TAOS2, TMEM16A, Ca2+-activated Cl- channel, and DOG1. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 80 citations in the literature describe the use of Anoctamin 1 antibodies in research. Immunohistochemistry is a widely used application for these antibodies. In addition, Western Blot is also a common application.