Anti-MPDZ antibodies are used in the immunodetection of the protein multiple PDZ domain crumbs cell polarity complex component. In humans, the canonical protein has a reported length of 2070 amino acid residues and a mass of 221.6 kDa. Its subcellular localization is in the cell membrane. Up to 4 different isoforms have been reported for this protein. It is found to be expressed in the heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. MPDZ is known to be a member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses. Synonyms for this target antigen include MUPP1, multiple PDZ domain protein, multi-PDZ domain protein 1, and HYC2. MPDZ gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of MPDZ antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.