Anti-QARS1 antibodies are used in the immunodetection of the protein glutaminyl-tRNA synthetase 1. In humans, the canonical protein has a reported length of 775 amino acid residues and a mass of 87.8 kDa. Its subcellular localization is in the cytoplasm. Up to 2 different isoforms have been reported for this protein. It is reported to be highly expressed in fetal cerebral cortex, particularly in the ventricular zone, inner subventricular zone, outer subventricular zone, and cortical plate. A member of the Class-I aminoacyl-tRNA synthetase protein family, QARS1 is known to be involved with brain development and the regulation of apoptosis. The QARS1 gene has been associated with the disease, Microcephaly. Synonyms for this target antigen include MSCCA, PRO2195, QARS, glutamine--tRNA ligase, glutamine-tRNA synthetase, and GLNRS. QARS1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.