Anti-MARCHF5 antibodies are used in the immunodetection of the protein membrane associated ring-CH-type finger 5. In humans, the canonical protein has a reported length of 278 amino acid residues and a mass of 31.2 kDa. Its subcellular localization is in the mitochondria and ER. It is reported to be expressed in the brain, heart, liver, lung, spleen, stomach, testis, skeletal and muscle. MARCHF5 is known to be involved with protein ubiquitination. Post-translational modifications have been described, including ubiquitination. Synonyms for this target antigen include MITOL, RNF153, E3 ubiquitin-protein ligase MARCHF5, E3 ubiquitin-protein ligase MARCH5, and MARCH-V. MARCHF5 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.