Anti-PLCB4 antibodies are used in the immunodetection of the protein phospholipase C beta 4. In humans, the canonical protein has a reported length of 1175 amino acid residues and a mass of 134.5 kDa. Up to 4 different isoforms have been reported for this protein. It is found to be highly expressed in the retina. PLCB4 is known to be involved with GPCR signaling pathways and the metabolism of lipids. The PLCB4 gene has been associated with the disease, Auriculocondylar syndrome. Synonyms for this target antigen include PI-PLC, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4, 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate, and ARCND2. PLCB4 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some PLCB4 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.