Anti-CTSG antibodies are used in the immunodetection of the protein cathepsin G. In humans, the canonical protein has a reported length of 255 amino acid residues and a mass of 28.8 kDa. Its subcellular localization is in the cell membrane, nucleus, lysosomes, cytoplasm, and is secreted. It is reported to be expressed in neutrophils. A member of the Peptidase S1 protein family, CTSG is known to be involved with the cellular response to lipopolysaccharides and cytokine-mediated signaling pathways. Post-translational modifications have been described, including glycosylation. The CTSG marker can be used to identify Promyelocytes.* Synonyms for this target antigen include CATG and CG. CTSG gene orthologs have been reported in the mouse, rat and chimpanzee species. A number of Ctsg antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4