Anti-SPART antibodies are used in the immunodetection of the protein spartin. In humans, the canonical protein has a reported length of 666 amino acid residues and a mass of 72.8 kDa. Its subcellular localization is in the cytoplasm. It is widely expressed across many tissue types. SPART is believed to be implicated in endosomal trafficking, or microtubule dynamics, or both. Post-translational modifications have been described, including ubiquitination. The SPART gene has been associated with the disease, Spastic paraplegia. Synonyms for this target antigen include TAHCCP1, spastic paraplegia 20 (Troyer syndrome), trans-activated by hepatitis C virus core protein 1, and SPG20. SPART gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of SPART antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.