Anti-DSPG3 antibodies enable researchers to detect and measure the DSPG3 antigen in biological samples. This target is a reported synonym of the EPYC gene, which encodes epiphycan. This protein is known to function in bone development, among other biological roles. The human version of DSPG3 has a canonical amino acid length of 322 residues and a protein mass of 36.6 kilodaltons. It is reported to be localized in the extracellular matrix and is secreted of cells and notably expressed in soft tissue, skin, placenta, and colon. DSPG3 is a member of the Small leucine-rich proteoglycan (SLRP) protein family.