Anti-VPS16 antibodies are used in the immunodetection of the protein VPS16 core subunit of CORVET and HOPS complexes. In humans, the canonical protein has a reported length of 839 amino acid residues and a mass of 94.7 kDa. Its subcellular localization is in the cytoplasmic vesicles, lysosomes, and membrane. Alternative splicing is reported to yield 2 different isoforms for this protein. It is ubiquitously expressed across many tissue types. A member of a the VPS16 protein family, VPS16 is reported to play a role in in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Synonyms for this target antigen include VPS16, CORVET/HOPS core subunit, vacuolar protein sorting 16 homolog, vacuolar protein sorting protein 16, and vacuolar protein sorting-associated protein 16 homolog.