Anti-HEPACAM2 antibodies are used in the immunodetection of the protein HEPACAM family member 2. In humans, the canonical protein has a reported length of 462 amino acid residues and a mass of 51.4 kDa. Its subcellular localization is in the Golgi and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is widely expressed across many tissue types. HEPACAM2 is known to be required during prometaphase for centrosome maturation. Post-translational modifications have been described, including N-glycosylation.
The HEPACAM2 marker can be used to identify Type 4 Medullary Thymic Epithelial Cells.* Synonyms for this target antigen include mitotic kinetics regulator. HEPACAM2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some HEPACAM2 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.
*HuBMAP Human Reference Atlas v1.4