Anti-SDK2 antibodies are used in the immunodetection of the protein sidekick cell adhesion molecule 2. In humans, the canonical protein has a reported length of 2172 amino acid residues and a mass of 239.4 kDa. Its subcellular localization is in the cell membrane. Up to 4 different isoforms have been reported for this protein. A member of the Sidekick protein family, SDK2 is reported to be an adhesion molecule that promotes lamina-specific synaptic connections in the retina and is specifically required for the formation of neuronal circuits that detect motion. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include protein sidekick-2 and sidekick homolog 2. SDK2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.