Anti-SCRIB antibodies are used in the immunodetection of the protein scribble planar cell polarity protein. In humans, the canonical protein has a reported length of 1630 amino acid residues and a mass of 174.9 kDa. Its subcellular localization is in the cell membrane and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is reported to be expressed in the kidney, skeletal muscles, liver, lung, breast, intestine, placenta and skin mainly in epithelial cells. A member of the LAP (LRR and PDZ) protein family, Scrib is known to be a scaffold protein involved in different aspects of polarized cell differentiation regulating epithelial and neuronal morphogenesis and T-cell polarization. Synonyms for this target antigen include SCRB1, SCRIB1, Vartul, oSCRIB, protein scribble homolog, and CRIB1. SCRIB gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish and chicken species. A number of Scrib antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.