Anti-ankyrin 3 antibodies are used for the immunodetection of the protein encoded by the ANK3 gene. In humans, the canonical protein has a reported length of 4377 amino acid residues and a mass of 480.4 kDa. Its subcellular localization is in the cell membrane, lysosomes and cytoplasm. Alternative splicing is reported to yield 5 different isoforms for this protein. It is reported to be expressed in the brain, neurons, muscles and other tissues. It is noted to be involved in neuronal development and cell division. The gene encoding this protein is implicated in Intellectual developmental disorder. Other names for this target antigen include MRT37, ankyrin 3, node of Ranvier (ankyrin G), and ANKYRIN-G. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 70 citations in the literature describe the use of ankyrin 3 antibodies in research. Western Blot is a widely used application for these antibodies. Immunocytochemistry and Immunofluorescence are also common applications.