Anti-BIK antibodies are used in the immunodetection of the protein BCL2 interacting killer. In humans, the canonical protein has a reported length of 160 amino acid residues and a mass of 18 kDa. Its subcellular localization is in the mitochondria. It is notably expressed in many tissues, such as the gallbladder and spleen. BIK is known to be involved with the apoptotic pathway and male gonad development. Post-translational modifications have been described, including protein cleavage. Synonyms for this target antigen include BP4, NBK, BCL2-interacting killer (apoptosis-inducing), apoptosis inducer NBK, apoptosis-inducing NBK, and BIP1. BIK gene orthologs have been reported in the mouse, rat and chimpanzee species. Over 80 citations in the literature describe the use of BIK antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunocytochemistry, Immunofluorescence, and Immunohistochemistry are also common applications.