Anti-PHEX antibodies are used in the immunodetection of the protein phosphate regulating endopeptidase X-linked. In humans, the canonical protein has a reported length of 749 amino acid residues and a mass of 86.5 kDa. Its subcellular localization is in the cell membrane. It is notably expressed in ovary. A member of the Peptidase M13 protein family, PHEX is a reported peptidase that cleaves SIBLING (small integrin-binding ligand, N-linked glycoprotein)-derived ASARM peptides, thus regulating their biological activity. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include HPDR1, HYP, HYP1, LXHR, PEX, XLH, phosphate-regulating neutral endopeptidase PHEX, and HPDR. PHEX gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some PHEX antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Flow Cytometry, and Immunofluorescence are also common applications.