Anti-SEM1 antibodies are used in the immunodetection of the protein SEM1 26S proteasome subunit. In humans, the canonical protein has a reported length of 70 amino acid residues and a mass of 8.3 kDa. Its subcellular localization is in the nucleus. It is reported to be expressed in limb bud, craniofacial primordia and skin. A member of the DSS1/SEM1 protein family, SEM1 is a known component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. Synonyms for this target antigen include DSS1, ECD, PSMD15, SHFD1, SHFM1, SHSF1, Shfdg1, and C7orf76. SEM1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of SEM1 antibodies have been mentioned in research publications and have associated citations. ELISA is a widely used application for these antibodies. Western Blot and Immunohistochemistry are also common applications.