Anti-PIGA antibodies are used in the immunodetection of the protein phosphatidylinositol glycan anchor biosynthesis class A. In humans, the canonical protein has a reported length of 484 amino acid residues and a mass of 54.1 kDa. Its subcellular localization is in the ER. Up to 3 different isoforms have been reported for this protein. It is notably expressed in many tissues, such as the appendix, testis, and adrenal gland. A member of the Glycosyltransferase group 1 protein family, PIGA is a known catalytic subunit of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynthesis. Synonyms for this target antigen include MCAHS2, NEDEPH, PNH1, phosphatidylinositol N-acetylglucosaminyltransferase subunit A, GLCNAC-PI synthesis protein, and GPI3. Some PIGA antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.