Anti-GTF2H2 antibodies are used in the immunodetection of the protein general transcription factor IIH subunit 2. In humans, the canonical protein has a reported length of 395 amino acid residues and a mass of 44.4 kDa. Its subcellular localization is in the nucleus. It is found to be widely expressed, with higher expression in skeletal muscle. A member of the GTF2H2 protein family, GTF2H2 is a known component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Synonyms for this target antigen include BTF2 p44, BTF2P44, T-BTF2P44, TFIIH, p44, and BTF2. GTF2H2 gene orthologs have been reported in the mouse and rat species. Some GTF2H2 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunofluorescence are also common applications.