Anti-Aph-1b antibodies enable researchers to detect and measure the Aph-1b antigen in biological samples. This target is a reported synonym of the APH1B gene, which encodes aph-1 homolog B, gamma-secretase subunit. This protein is known to function in the Notch signaling pathway, among other biological roles. The human version of Aph-1b has a canonical amino acid length of 257 residues and a protein mass of 28.5 kilodaltons, although 2 isoforms have been identified. It is reported to be localized in the membrane of cells. Aph-1b is a member of the APH-1 protein family.