Anti-PAPOLG antibodies are used in the immunodetection of the protein poly(A) polymerase gamma. In humans, the canonical protein has a reported length of 736 amino acid residues and a mass of 82.8 kDa. Its subcellular localization is in the nucleus. Up to 2 different isoforms have been reported for this protein. It is reported to be highly expressed in the testis, and weakly in other tissues. A member of the Poly(A) polymerase protein family, PAPOLG is known to be important for the post-transcriptional adenylation of the 3'-terminal of mRNA precursors and several small RNAs including signal recognition particle (SRP) RNA, nuclear 7SK RNA, U2 small nuclear RNA, and ribosomal 5S RNA. Synonyms for this target antigen include SRP RNA 3' adenylating enzyme/pap2, SRP RNA 3'-adenylating enzyme, SRP RNA-adenylating enzyme, neo-PAP, neo-poly(A) polymerase, and PAP-gamma. PAPOLG gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Some PAPOLG antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.