Anti-RNF186 antibodies are used in the immunodetection of the protein ring finger protein 186. In humans, the canonical protein has a reported length of 227 amino acid residues and a mass of 24.1 kDa. Its subcellular localization is in the ER. Among its functions, RNF186 is involved with the apoptotic pathway. Post-translational modifications have been described, including ubiquitination. Synonyms for this target antigen include E3 ubiquitin-protein ligase RNF186.