Anti-ORC4 antibodies are used in the immunodetection of the protein origin recognition complex subunit 4. In humans, the canonical protein has a reported length of 436 amino acid residues and a mass of 50.4 kDa. Its subcellular localization is in the nucleus. Up to 3 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the ORC4 protein family, ORC4 is a known component of the origin recognition complex (ORC) that binds origins of replication. The ORC4 gene has been associated with the disease, Meier-Gorlin syndrome. Synonyms for this target antigen include ORC4P, origin recognition complex, subunit 4 homolog, and ORC4L. ORC4 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some ORC4 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.