Anti-RS1 antibodies are used in the immunodetection of the protein retinoschisin 1. In humans, the canonical protein has a reported length of 224 amino acid residues and a mass of 25.6 kDa. Its subcellular localization is in the cell membrane and is secreted. It is notably expressed in the retina. RS1 is known to bind negatively charged membrane lipids, such as phosphatidylserine and phosphoinositides (By similarity). The RS1 gene has been associated with the disease, Retinoschisis juvenile X-linked. Synonyms for this target antigen include XLRS1, retinoschisin, X-linked juvenile retinoschisis protein, and RS. RS1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some RS1 antibodies may have been used in research and have associated citations. ELISA is a widely used application for these antibodies. In addition, Western Blot is also a common application.