Anti-MAGED2 antibodies are used in the immunodetection of the protein MAGE family member D2. In humans, the canonical protein has a reported length of 606 amino acid residues and a mass of 65 kDa. Alternative splicing is reported to yield 2 different isoforms for this protein. It is widely expressed across many tissue types. MAGED2 is reported to regulate the expression, localization to the plasma membrane and function of the sodium chloride cotransporters SLC12A1 and SLC12A3, two key components of salt reabsorption in the distal renal tubule. Synonyms for this target antigen include BARTS5, BCG-1, BCG1, HCA10, melanoma-associated antigen D2, and 11B6.