Anti-MBTPS1 antibodies are used in the immunodetection of the protein membrane bound transcription factor peptidase, site 1. In humans, the canonical protein has a reported length of 1052 amino acid residues and a mass of 117.7 kDa. Its subcellular localization is in the ER and Golgi. It is widely expressed across many tissue types. A member of the Peptidase S8 protein family, MBTPS1 is reported to be a serine protease that cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4: known substrates include SREBF1/SREBP1, SREBF2/SREBP2, BDNF, GNPTAB, ATF6, ATF6B and FAM20C. Synonyms for this target antigen include S1P, SEDKF, SKI-1, membrane-bound transcription factor site-1 protease, endopeptidase S1P, and PCSK8. MBTPS1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of MBTPS1 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunofluorescence are also common applications.