Anti-LRGUK antibodies are used in the immunodetection of the protein leucine rich repeats and guanylate kinase domain containing. In humans, the canonical protein has a reported length of 825 amino acid residues and a mass of 93.6 kDa. Its subcellular localization is in the cytoplasmic vesicles and cytoplasm. LRGUK is known to be involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Synonyms for this target antigen include leucine-rich repeat and guanylate kinase domain-containing protein. LRGUK gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some LRGUK antibodies may have been used in research and have associated citations. Immunofluorescence is a widely used application for these antibodies. Western Blot, Immunocytochemistry, and Immunohistochemistry are also common applications.