Anti-parvin beta antibodies are used for the immunodetection of the protein encoded by the PARVB gene. In humans, the canonical protein has a reported length of 364 amino acid residues and a mass of 41.7 kDa. Its subcellular localization is in the cell membrane and cytoplasm. Alternative splicing is reported to yield 3 different isoforms for this protein. It is reported to be highly expressed in the heart and skeletal muscle. A member of the Parvin protein family, it is a reported adaptor protein that plays a role in integrin signaling via ILK and in activation of the GTPases CDC42 and RAC1 by guanine exchange factors, such as ARHGEF6. Other names for this target antigen include beta-parvin, affixin, and CGI-56. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of parvin beta antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.