Anti-PLPP5 antibodies are used in the immunodetection of the protein phospholipid phosphatase 5. In humans, the canonical protein has a reported length of 264 amino acid residues and a mass of 29.5 kDa. Its subcellular localization is in the cell membrane. Up to 4 different isoforms have been reported for this protein. It is ubiquitously expressed across many tissue types. A member of the PA-phosphatase related phosphoesterase protein family, PLPP5 is known to be involved with the metabolism of lipids.
The PLPP5 marker can be used to identify Transitional Immature B Cells.* Synonyms for this target antigen include diacylglycerol pyrophosphate phosphatase-like 1, phosphatidate phosphatase PPAPDC1B, phosphatidic acid phosphatase type 2 domain containing 1B, and diacylglycerol pyrophosphate like 1. PLPP5 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some PLPP5 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunofluorescence are also common applications.
*HuBMAP Human Reference Atlas v1.4