Anti-NIF3L1 antibodies are used in the immunodetection of the protein NGG1 interacting factor 3 like 1. In humans, the canonical protein has a reported length of 377 amino acid residues and a mass of 42 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the GTP cyclohydrolase I type 2/NIF3 protein family, NIF3L1 is believed to function as a a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation. Synonyms for this target antigen include GTP cyclohydrolase I, NIF3 (Ngg1 interacting factor 3, S.pombe homolog)-like 1, NIF3 NGG1 interacting factor 3-like 1, and NIF3-like protein 1. NIF3L1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some NIF3L1 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.