Anti-glycoprotein 2 antibodies are used for the immunodetection of the protein encoded by the GP2 gene. In humans, the canonical protein has a reported length of 537 amino acid residues and a mass of 59.5 kDa. Its subcellular localization is in the cell membrane and is secreted. Alternative splicing is reported to yield 4 different isoforms for this protein. It is notably expressed in the pancreas. It is known to function as a intestinal M-cell transcytotic receptor specific for type-I-piliated bacteria that participates in the mucosal immune response toward these bacteria. Other names for this target antigen include pancreatic secretory granule membrane major glycoprotein GP2, glycoprotein 2 (zymogen granule membrane), pancreatic zymogen granule membrane associated protein GP2, and ZAP75. Gene orthologs have been identified in the mouse, rat, bovine and chimpanzee species. A number of glycoprotein 2 antibodies have been mentioned in research publications and have associated citations. Immunohistochemistry is a widely used application for these antibodies. ELISA, Western Blot, Immunocytochemistry, and Immunofluorescence are also common applications.