Anti-CX3CL1 antibodies are used in the immunodetection of the protein C-X3-C motif chemokine ligand 1. In humans, the canonical protein has a reported length of 397 amino acid residues and a mass of 42.2 kDa. Its subcellular localization is in the cell membrane and is secreted. It is reported to be expressed in the seminal plasma, endometrial fluid and follicular fluid. A member of the Intercrine delta protein family, CX3CL1 is a reported chemokine that acts as a ligand for both CX3CR1 and integrins ITGAV:ITGB3 and ITGA4:ITGB1. Post-translational modifications have been described, including O-glycosylation and protein cleavage. Synonyms for this target antigen include C3Xkine, CXC3, CXC3C, NTN, NTT, SCYD1, fractalkine, and ABCD-3. CX3CL1 gene orthologs have been reported in the mouse, rat, bovine, chimpanzee and chicken species. Over 170 citations in the literature describe the use of CX3CL1 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.