Anti-DEAD-box helicase 42 antibodies are used in the immunodetection of the protein encoded by the DDX42 gene. In humans, the canonical protein has a reported length of 938 amino acid residues and a mass of 103 kDa. Its subcellular localization is in the nucleus and cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. It is reported to be expressed in several cell lines. A member of the DEAD box helicase protein family, it is known to be involved with protein localization and the regulation of apoptosis. Other names for this target antigen include RHELP, RNAHP, SF3B8, SF3b125, ATP-dependent RNA helicase DDX42, and DDX42P.