Anti-TRAF2 antibodies are used in the immunodetection of the protein TNF receptor associated factor 2. In humans, the canonical protein has a reported length of 501 amino acid residues and a mass of 55.9 kDa. Its subcellular localization is in the cytoplasm. Up to 4 different isoforms have been reported for this protein. A member of the TNF receptor-associated factor protein family, TRAF2 is reported to regulate activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis. Synonyms for this target antigen include RNF117, TRAP, TRAP3, E3 ubiquitin-protein ligase TRAF2, RING-type E3 ubiquitin transferase TRAF2, and MGC:45012. TRAF2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 200 citations in the literature describe the use of TRAF2 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.