Anti-FECH antibodies are used in the immunodetection of the protein ferrochelatase. In humans, the canonical protein has a reported length of 423 amino acid residues and a mass of 47.9 kDa. Its subcellular localization is in the mitochondria. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the Ferrochelatase protein family, Fech is known to catalyze the ferrous insertion into protoporphyrin IX. The FECH gene has been associated with the disease, Protoporphyria. Synonyms for this target antigen include EPP1, FCE, ferrochelatase, mitochondrial, heme synthase, heme synthetase, and EPP. FECH gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of Fech antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.