Anti-MAGEA6 antibodies are used in the immunodetection of the protein MAGE family member A6. In humans, the canonical protein has a reported length of 314 amino acid residues and a mass of 34.9 kDa. It is reported to be expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes. Among its functions, MAGEA6 is involved with autophagy pathways and the regulation of transcription. Post-translational modifications have been described, including ubiquitination. Synonyms for this target antigen include MAGE-3b, MAGE3B, MAGE6, melanoma-associated antigen 6, MAGE-6 antigen, and CT1.6.