Anti-RNF181 antibodies are used in the immunodetection of the protein ring finger protein 181. In humans, the canonical protein has a reported length of 153 amino acid residues and a mass of 17.9 kDa. It is found to be widely expressed, with highest levels in the liver and heart and lowest levels in the brain and skeletal muscle. A member of the RNF181 protein family, RNF181 is known to be involved with protein ubiquitination. Post-translational modifications have been described, including ubiquitination. Synonyms for this target antigen include E3 ubiquitin-protein ligase RNF181, RING-type E3 ubiquitin transferase RNF181, and HSPC238. RNF181 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish and chimpanzee species. A number of RNF181 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.