Anti-MARCKS antibodies are used in the immunodetection of the protein myristoylated alanine rich protein kinase C substrate. In humans, the canonical protein has a reported length of 332 amino acid residues and a mass of 31.6 kDa. Its subcellular localization is in the cytoplasm. A member of the MARCKS protein family, it is known to be involved with the apoptotic pathway and nervous system development. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include MACS, PRKCSL, myristoylated alanine-rich C-kinase substrate, myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L), and 80K-L.