Anti-GLRA1 antibodies are used in the immunodetection of the protein glycine receptor alpha 1. In humans, the canonical protein has a reported length of 457 amino acid residues and a mass of 52.6 kDa. Its subcellular localization is in the cell membrane. Up to 2 different isoforms have been reported for this protein. A member of the Ligand-gated ion channel (TC 1.A.9) protein family, GLRA1 is known to be involved with chemical synaptic transmission. Post-translational modifications have been described, including glycosylation. The GLRA1 gene has been associated with the disease, Hyperekplexia. Synonyms for this target antigen include STHE, glycine receptor subunit alpha-1, glycine receptor 48 kDa subunit, glycine receptor strychnine-binding subunit, and HKPX1. GLRA1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 130 citations in the literature describe the use of GLRA1 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.