Anti-ARL2 antibodies are used in the immunodetection of the protein ADP ribosylation factor like GTPase 2. In humans, the canonical protein has a reported length of 184 amino acid residues and a mass of 20.9 kDa. Its subcellular localization is in the nucleus, mitochondria, and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the Arf protein family, ARL2 is reported to be a small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). Synonyms for this target antigen include MRCS1, ADP-ribosylation factor-like protein 2, ADP-ribosylation factor-like 2, and ARFL2. ARL2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish and chimpanzee species. A number of ARL2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.