R-Spondin 2, or, RSPO2, is a human gene. Other names include: R-spondin-2; hRspo2; Roof plate-specific spondin-2; CRISTIN2. The encoded protein has an amino acid length of 243 and a mass of 28.3 kDa. Other isoforms may exist. R-Spondin 2 is a member of the R-spondin family. This gene shares homology with other species, including: Mouse, Rat, Zebrafish, Frog, Chicken.