Anti-GCD antibodies are used in antigen-specific immunodetection in biological samples. The target GCD is a known alias name of the protein glutaryl-CoA dehydrogenase, encoded by the GCDH gene in humans. This 438-amino acid residue protein is known to catalyze the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It is localized to the mitochondria of the cell. It is reported to be widely expressed in many tissue types.