Anti-NPHP1 antibodies are used in the immunodetection of the protein nephrocystin 1. In humans, the canonical protein has a reported length of 732 amino acid residues and a mass of 83.3 kDa. Its subcellular localization is in the cell junctions and cytoplasm. Up to 4 different isoforms have been reported for this protein. It is reported to be widely distributed with highest levels in pituitary gland, spinal cord, thyroid gland, testis, skeletal muscle, lymph node and trachea. A member of the Nephrocystin-1 protein family, NPHP1 is known to be involved with cytoskeleton organization and cell adhesion. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include JBTS4 and NPH1. NPHP1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some NPHP1 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.